Code AOE-1 / 160 Capsules / Price: $39.80
In our 30+ years, this is the most important,
needful formula we've ever put in a capsule.
Complete Vit. D3, K2-MK7, Zinc, Magnesium, Selenium,
Boron, Molybdenum, and Copper Formula
See: Supplement Facts

ne of the principle obstacles that we encounter in our work are "low grade" or subclinical nutritional deficiencies -- specifically, vitamins, minerals, amino acids, EFA's, etc. It sounds innocuous, but the effects of these subclinical conditions devastate a large percentage of people. What's worse is that the orthodox medical establishment is completely obtuse if not negligently ignorant (some might say criminally so) of its existence. What makes this unusual is that most diseases are caused by nutritional deficiency.1 The proof of this ignorance is that as orthodox and mainstream a source as Wikipedia brands orthomolecular medicine, which incorporates many of the ideas I'm going to talk about, as quackery.2
In other words, what we're discussing are deficiencies that do not rise to the level of the disease most commonly associated with a particular deficiency, but bad enough to contribute to many other disease conditions.3 For example, every medical student is taught the results of extreme deficiency of essential nutrients: with Vitamin C, it's scurvy; Vitamin D, rickets; Vitamin B1, beriberi; Vitamin B3, pellagra; etc. But these are only the results of the most extreme deficiencies in these nutrients.
In 2004, I discussed the horrific effects of even mild deficiency of Vitamin C -- something that Dr.Linus Pauling, winner of the Nobel Prize for Medicine, called hypoascorbemia. I cover this extensively in Chapter 4 of Meditopia. I now understand that "hypocholecalciferia" -- if you will -- is every bit as dangerous. Moreover, the degree to which this phenomenon is underappreciated can be found when one realizes that the RDA (U.S. Recommended Daily Allowance) for Vitamin D is 400 to 800 IU, but the "optimal dose" is closer to 30,000 IU, or roughly 50 times higher, and that there are people who have taken 3,000,000 IU per day for extended periods without ill-effect, which is 5,000 times higher! The absurdity of the official numbers are accentuated when you realize that the human body can product about 20,000 IU on its own, if you stay out in the sun for 30 minutes with most of your skin exposed. (By the way, it is important at this stage that you clearly understand the difference between the different forms of Vitamin D. There are five different types. For the rest of this page, when I refer to Vitamin D, I'm referring to Vitamin D3, the preferred therapeutic form.)4
Are you beginning to grasp the absurdity of it all yet? Maybe, just a little? If we extrapolate from these basic facts, it means that the official position of medical and nutrition community is that it is very dangerous to your health to spend even more than one minute per day outside, exposed to the sun. That's right. Totally ludicrous? Are authorities ever embarrassed that they put these numbers out there? Of course not. How many health authorities will tell you with a straight face that "the mask" will protect you from CoVid, when the evidence is overwhelming that chronic mask use is dangerous to your health? 5 Would it be even 1%? I doubt it.

Books on the subject of recent D3 findings have been gaining in popularity over the past 10 years. If you look go to Amazon.com and type in Vitamin D3 in the search bar (first choose "Books" as your category), you get over 370 titles, and the majority of these focus on recent findings. Strangely, there is a disconnect between the products that vitamin manufacturers are making and selling, and the optimal formulations that the scientific literature clearly dictates that they should be making. (Some prominent titles are provided in the right column.)
Here's a good example:
The market is awash with Vitamin D3 supplements (often with K2, which is the first co-factor I discuss below) in the 1,000 to 5,000 IU value range. The scientific literature strongly suggests that the optimal dosage is anywhere from 25,000 IU daily (the dosage that Vitamin D3 researcher and author, Jeff Bowles, openly admits he's been taking for years), to let us say, 30,000 IU daily (the dosage that Dr. Somerville has been recommending to all his patients for years, based on his own extensive research and experience, both personal and professional.).
This begs the question, "Why the lower dosages?" And the answer is that it is more profitable. Now, of course, the argument could be made, "Just take five 5,000 IU caps to get to the 25,000 IU, or ten 5,000 IU caps to get to 50,000 IU." But why would you do that when you could load up a small #1 capsule with 200 mg. of Vitamin C (500,000 IU per gram variety), yielding 100,000 IU, and still have room left over for a full gram of Vitamin K2/MK7?
It doesn't make any sense.

---

But even this institutionalized "low dosing" on the part of vitamin manufacturers doesn't address the larger issue of co-factor exclusion to the detriment of the consumer. (We include, in this formula, what the literature shows are the most critical co-factors -- but we respect that others have different opinions as to the most necessary Vitamin D co-factors.)
Orthodoxists claim that "high dosing" with Vitamin D can be potentially dangerous -- a claim that helped produce the laughably low "official figures" in the first place. The vast majority of medical doctors in the world, trusting what they are taught in medical school -- maybe I should say "not taught," are fully onboard with this false narrative. What they failed to add is that this danger can be removed by adding co-factors. Why is this important? Because Vitamin D3 "high dosing" -- or perhaps I should say, "proper dosing" -- produces deficiencies in certain essential co-factors, in the absence of an optimal diet. Nutritional expert, Dr. Carolyn Dean, M.D., N.D., echoing the advice of the Vitamin D Council, specifies four: magnesium, zinc, Vitamin K2, boron, and "a tiny amount of Vitamin A". (All of these are included in AO Essentials One, except for Vitamin A, which you can easily get in optimal amounts from carrots, greens, milk, and a variety of other foods.) We also add selenium (which most people are also deficient in), molybdenum, and copper (the latter to balance out the zinc).
From February 2, 2020 until February 2, 2021 -- precisely one year -- I maintained a daily CoVid blog, which attempted to get to the bottom of this global, world-changing phenomenon. Out of that evolution of thought and discovery came supplemental recommendations based on the clinical observation that most CoVid patients were deficient in Vitamin D, zinc, and magnesium -- some quite severely in one or more of these nutrients. These observations worked their way into an advisory page I wrote, called Coronavirus: Essential Self-Defense Against Infection.
Well before CoVid entered the popular lexicon, the relationship between Vitamin D and its best-known co-factors, zinc, magnesium, and boron, were already well-established. The orthodox community had, for many years, advised against taking "too much Vitamin D to avoid its toxicity." With time it was discovered that high dose Vitamin D, taken therapeutically, could cause a depletion of magnesium and zinc to dangerous levels. It wasn't the Vitamin D itself that was toxic. Whether by accident, ignorance, or malicious intent, orthodox chose to confuse cause and effect. The problem was the depletion of critically important magnesium and zinc, minerals for which the human body increases drawdown when Vitamin D intake is increased to "optimal therapeutic levels" OR which often accompanies states of Vitamin D deficiency itself.
Jeff Bowles, after reviewing 52,000 scientific studies on Vitamin D, a project that consumed many years, came to the conclusion that NOBODY should sell high dose Vitamin D without K2. Out of this stern advisement came the massive coupling of these two vitamin supplements on vitamin shelves. But I will go one step farther: I have come to believe that it isn't smart to take Vitamin D3/K2 without adding zinc, magnesium, and boron -- at a minimum. Again, this matches the advise of the Vitamin D Council. 6
With these nutrient interdependencies in mind, let's review the Vitamin D co-factors that are included in AO Essentials 1.

Vitamin K was discovered in 1929, and there are two forms: K1 (phylloquinone) and K2 (menaquinone) -- the former is found in plant foods like leafy greens, the latter, in animal and fermented foods, and has been established as being a superior form.7 If Vitamin D3 high dose supplementation is adopted without an adequate amount of Vitamin K in the diet, then the bone building and strengthening attributes of D3 can be redirected to calcification of blood vessels and kidneys. The solution is easy, but it is still a solution that must be employed. This is especially true since so many people are lacking in it. Fully 97% of a sample of otherwise healthy subjects were found to be deficient in Vitamin K2 in a recent study. However, the distribution of this deficiency favors the elderly.8
Vitamin K2 in critical to blood clotting, heart health. bone health, cavity prevention, and the optimization of Vitamin D3 -- a fact now so well-known that it explains why D3 and K2 are so frequently coupled by vitamin manufacturers.

Zinc is a critical nutrient largely disregarded by modern medicine. Although zinc discovery and use goes back at least into Greek antiquity, nutritional zinc deficiency in humans wasn't discovered or recognized until 1961 -- long after its importance to plants and other animals was firmly established.9 Your author and half of Alpha Omega's customers are older than that!
In my March, 2020 CoVid Blog, I reported that an astonishing correlation was found between the symptoms of CoVid and those of zinc deficiency -- the latter having been well-established.10
Strangely, Jeff Bowles has also uncovered countless examples and obscure studies showing a correlation between higher dosing of Vitamin D and zinc, as well as our next nutrient, magnesium. If you do a search online for this information, you find that it has largely been censored.

For all our of 30+ yeaer history, Alpha Omega Labs has never pushed magnesium supplementation -- largely because its nutritional properties AND its abundance in certain foods has been well-established.11 Magnesium deficiency is all too often the result of poor diet.

As in the case of zinc and other essential minerals, the symptoms of magnesium deficiency is well-established.12 However, you shouldn't "skip on magnesium" if you're supplementing with Vitamin D. Nor do we believe that magnesium supplementation should be used as a excuse to skip on magnesium-heavy foods in the general diet. There ARE indigenous groups who have personal diets with as much as 3,000 mg. per day.



Selenium is an essential nutrient whose benefits didn't begin to be recognized until 1957. The "official" recommended daily allowance is only from 20 to 70 micrograms (per day) are required, however, its benefits are even recognized by orthodoxy.13 It is included in AO Essentials 1 not because it is a Vitamin D co-factor -- it's not -- but because many people are deficient in selenium, as well. We include just a small amount to prevent insufficiency because selenium has a narrower range of optimal intake than many other minerals.
For years Dr. Joel Wallach wrote books and gave interviews about how miraculous selenium works in treating cardiomyopathy.14 But he stated in his other written works that selenium helps with dozens of other health conditions. Additionally, I worked with the late Dr. Neville Solomon in Guayaquil for several years before his untimely death in 2011. In his own clinical work, Neville found that VERY few cancer patients did not respond well to selenium supplementation, not because selenium is a cancer cure, but because so many people are deficient.


Boron is an essential nutrient for which, quite paradoxically, the USDA and other authorities have NOT established a recommended daily allowance. This is strange, because they have no problems establishing its upper safety limit -- (see chart below).15.
Over the years, I've encountered many studies and anecdotal reports, both, where people derived tremendous benefit from taking borax (sodium borate). Normally people associate borax with laundry detergent, but it is an important Vitamin D co-factor, and as stated above, a essential mineral in its own right.
Years ago, I worked with a botanist who told me, "There are 16 essential minerals that plants need to survive. Everyone knows about NPK (nitrogen, phosphorus, and potassium), but little is said about the other 13. When you get down to the last two -- boron and molybdenum -- which plants only need in micrograms, you find that they are completely unappreciated. Maybe because despite how critical they are, plants need so very little. Some day, they'll discover that humans have the same relationship with them."

Molybdenum is not added to the formula as a co-factor. It is added, because many of the bone disease and neurological complaints we get suggest possible deficiency. Because testing for molybdenum is rare, it is indeterminable at this point, from an epidemiological perspective, whether or not molybenum deficiency is a broader problem. I do find it intereseting, speaking as a grower, that molybdenum deficiency has become a much more popular topic of discussion in the plant world.



Copper is another essential mineral that is often coupled with zinc supplementation, in order to balance the formula. The reason has been well-established: just as Vitamin D creates demands for magnesium and zinc on the body, so zinc supplementation, in turn, induces drawdown on copper. We do not recommend any copper supplementation -- ever -- in the absence of added zinc. However, since zinc blocks copper absorption, add roughly 2% (1:50 ratio) cooper-to-zinc is well supported in the nutraceutical literature.

---

Vit. D3 & Co-Factors
Popular Literature

This little gem dates to 2013, but versions go back to 2010. If you have a mind that prefers to stick to purely provable scientific fact, you'll find the author's approach obnoxiously bombastic. And yet, the author provides valuable insights that I had not seen in all the literature on this subject to this point. The most valuable part of the book is the clear explanation of winter hibernation syndrome and its effects, and summarized information consolidating the examination of over 52,000 studies published on the known benefits of Vitamin D3.
The book has sold over 300,000 copies, and basically launched the author's career as a Vit. D evangelist. There are so many valuable insights, and one can readily forgive the shoddy typography, formatting, syntax, etc.

Dr. Somerville is a paraplegic medical doctor practicing out of Laredo, Texas. This book, written in 2018, summarizes the effects that the Dr. Somerville has witnessed in thousands of his patients over an eight year period, beginning with his own miraculous healing. Though not as sensationalistic as Bowles work, it is more credible.
In just 136 pages, the broad spectrum of disorders that are aided by the use of high dose D3 is covered. The closing three chapters do a great job focussing on respiratory issues, MS, and weight loss.

Jeff Bowles makes a compelling argument that no one should take high dose Vitamin D3 without concurrently taking Vitamin K2, MK7 variety. He is the biggest reason that so many Vitamin D3 formulas also contain K2. He didn't figure all of this out by himself. He acknowledges the influence of Dr. Kate Rheaume-Bleue and her presentation in this book.

Like Dr. Somerville, M.D. above, this author, Sarfraz Zaidi, M.D., provides valuable clinical insights on the role of Vitamin D in mitigating and treating diseases, many of which do not respond well to orthodox approaches.
He points out the important role of Vitamin D in treating viral conditions, something I pointed out on my own commentary on CoVid.

I hate the cover. If they gave out Pulitzer Prizes for obnoxious, pretentious titles, this one would be a contender. I was so turned off by the title, I almost didn't read it. However, having read Bowles previous book on the subject (see above), I knew I had to read this sequel.
Of particular importance in this volume is a reiteration on how ridiculously low the "official" recommendations for daily allowance of Vitamin D are (400 to 800 IU), and co-factors that mitigate the supposed dangers of high dose Vitamin D that are instilled into every medical student.

Vitamin D therapy -- that is -- taking orthomolecular values, or high doses of Vitamin D, draws heavily on the body's Vitamin K2 and magnesium stores. It is important to understand the role of magnesium in the process, and why magnesium is such a vital co-factor for this therapeutic approach. Dr. Dean does an excellent job of explaining why magnesium deficiency is every bit as dangerous as Vitamin D3 deficiency.

Supplement Facts

Serving Size: 1 Capsule (per day)
Servings Per Container: 120

---

---

Vitamin D3 (cholecalciferol)	60 mg	3,750%
(@500,000 IU/g = 30,000 IU)

---

Vitamin K2 (as menaquinone-7)

1,200 mcg.

1,000%

---

Zinc (acetate/gluconate)

70 mg.

637%

---

Magnesium (malate/citrate)

300 mg.

78%

---

Selenium (L-selenomethionine)

300 mcg.

390%

---

Boron (amino acid chelated)

20 mg.

**

---

Molybdenum (glycinate chelate)

250 mcg.

332%

---

Copper (glycinate)

2 mg.

220%

---